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1. Hydration at Swelling Ang unang hakbang sa mekanismo ng pagpapalapot ng HEC ay ang hydration. Kapag ang HEC ay nilagay sa tubig, ang mga hydroxyl group (–OH) sa mga molekula nito ay nakikipag-ugnayan sa mga molekula ng tubig. Ito ay nagiging sanhi ng pagsipsip ng tubig at pagbubuo ng isang gel-like na estruktura. Ang prosesong ito ay nagpapalaki sa laki ng mga HEC particles, na nagreresulta sa pagtaas ng viscosidad ng solusyon.
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When considering the safety of HPMC, it is essential to examine its regulatory status. HPMC is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is approved for use in food products. The FDA has reviewed data pertaining to HPMC’s safety and concluded that its use in food and pharmaceutical applications poses minimal health risks. The European Food Safety Authority (EFSA) also supports this assessment, allowing specific levels of HPMC in food products within the EU.
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