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HPMC viscosity tables categorize the polymer based on its viscosity in aqueous solutions, often measured at a specific concentration (commonly 2% w/v) and temperature (typically 20°C). The table includes grades of HPMC, such as low, medium, and high viscosity, with corresponding viscosity values. These grades allow formulators to select the appropriate type of HPMC for their specific needs.
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HPMC also plays a vital role in clinical trials. The design and management of clinical trials generate extensive data that can be challenging to analyze. HPC can streamline this process by utilizing predictive modeling and simulations to identify optimal trial protocols, ensuring that researchers allocate their resources effectively. Furthermore, HPC can facilitate real-time data analysis during trials, enabling quicker adjustments based on emerging trends, which can ultimately accelerate the timeline for bringing new therapies to market.
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1. Solubility in Water One of the most critical aspects of the HPMC solubility chart is its water solubility. HPMC is hydrocolloidal, meaning it forms gels or viscous solutions upon contact with water. The degree of substitution (DS) determines how well HPMC dissolves in water. Generally, HPMC with a higher methoxy or hydroxypropyl content shows greater solubility in cold water, making it suitable for various applications, including thickening agents and stabilizers.
hpmc solubility chart

Allergic reactions to HPMC are rare but possible. Some people may experience skin irritations, rashes, or respiratory issues after exposure or ingestion of products containing HPMC. It is crucial for individuals with known allergies to cellulose derivatives or similar compounds to approach HPMC consumption with caution. If any allergic symptoms occur, such as hives, difficulty breathing, or swelling of the face and throat, immediate medical attention should be sought.
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